Cancer Prevention, Screening & Risk Assessment David S. Alberts, MD, Mary Klein Buller, MA, Ernest Rosenbaum, MD, Malin Dollinger, MD, and Guy Newell, MD Most of our lives have been, or will be, touched by cancer. But there are positive measures we can take to prevent or survive this disease. More than one million new cases of cancer are diagnosed in the U.S. annually. As the second leading cause of death after heart disease, cancer claims the lives of more than half a million Americans each year. Although that translates into one death from cancer every minute, there is reason for optimism. Significant advances in the prevention, early detection and treatment of several cancers have enabled half of all patients with cancer to survive. More than 8 million Americans alive today with a history of cancer can attest to recent successes.